lost_polypeptide

SO:0002395

Definition: A complete loss of polypeptide (i.e. protein) expression, as a consequence of a variant in the gene.

Comments and references

Added at the request of Melissa Landrum of the NCBI on 1 Aug 2025 (see GitHub issue #657).

Definition references: PMID:34413497

Synonyms

ScopeValue
exactabsent polypeptide
exactabsent protein
exactlost polypeptide
exactlost protein

Identifiers and subsets

Accession: SO:0002395

Persistent URL: http://purl.obolibrary.org/obo/SO_0002395

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2025-08-01 in commit 47b5048

Most recent Git-era change: 2025-08-01 in commit c754779

Number of changes: 2

Ontology neighborhood diagram

Ontology neighborhood for SO:0002395 Ontology neighborhood graph for SO:0002395 lost_polypeptide. Parent, child, and related nodes can be activated to open their term pages. SO:0002317 absent_gene_product SO:0002317 absent_gene_product SO:0002395 lost_polypeptide SO:0002395 lost_polypeptide
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

None recorded in the current release neighborhood.

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2025-08-01editedTerm stanza touched in repository historyc754779
2025-08-01createdTerm introduced into the editable ontology history
Initial label: lost_polypeptide
Initial definition captured.
Initial parent: SO:0002317
47b5048