SO:0002376 - H_ACA_box_snoRNA

H_ACA_box_snoRNA_gene

SO:0002376

Definition: A gene that codes for H_ACA_box_snoRNA. Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

Comments and references

Added at the request of Steven Marygold. See GitHub Issue #519 (https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/519). Added citations. See GitHub Issue #565.

Definition references: PMID:12457565, PMID:22065625

Synonyms

Scope	Value
exact	box H/ACA snoRNA gene, H ACA box snoRNA gene, H/ACA box snoRNA gene

Identifiers and subsets

Accession: SO:0002376

Persistent URL: http://purl.obolibrary.org/obo/SO_0002376

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2021-11-18 in commit 36b6ede

Most recent Git-era change: 2021-11-18 in commit 9ae593a

Number of changes: 2

Ontology neighborhood diagram

The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

SO:0001267 - snoRNA_gene

Children

SO:0002380 - pseudouridylation_guide_snoRNA_gene

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

Date	Change	Summary	Evidence
2021-11-18	edited	Term stanza touched in repository history	`9ae593a`
2021-11-18	created	Term introduced into the editable ontology history Initial label: H_ACA_box_snoRNA_gene Initial definition captured. Initial parent: SO:0001267	`36b6ede`