SO:0002375 - C_D_box_snoRNA

C_D_box_snoRNA_gene

SO:0002375

Definition: A gene that codes a C_D_box_snoRNA. Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'.

Comments and references

Added at the request of Steven Marygold. See GitHub Issue #519 (https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/519). Added citations. See GitHub Issue #565.

Definition references: PMID:12457565, PMID:22065625

Synonyms

Scope	Value
exact	box C/D snoRNA gene, C D box snoRNA gene, C/D box snoRNA gene

Identifiers and subsets

Accession: SO:0002375

Persistent URL: http://purl.obolibrary.org/obo/SO_0002375

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2021-11-18 in commit 36b6ede

Most recent Git-era change: 2021-11-18 in commit 9ae593a

Number of changes: 2

Ontology neighborhood diagram

The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

SO:0001267 - snoRNA_gene

Children

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

Date	Change	Summary	Evidence
2021-11-18	edited	Term stanza touched in repository history	`9ae593a`
2021-11-18	created	Term introduced into the editable ontology history Initial label: C_D_box_snoRNA_gene Initial definition captured. Initial parent: SO:0001267	`36b6ede`