Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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altered_gene_product_level

SO:0002314

Definition: A sequence variant that alters the level or amount of gene product produced. This high level term can be applied where the direction of level change (increased vs decreased gene product level) is unknown or not confirmed.

Comments and references

Added as per request from Ang Roberts as part of GenCC November 2020. See Issue Request #501 (https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/501). Updated definition 17 Feb 2023 along with updates from GenCC. See Issue Request #612.

Definition references: GenCC:AR

Synonyms

ScopeValue
exactaltered gene product level
exactaltered transcription level
exactaltered_transcription_level

Identifiers and subsets

Accession: SO:0002314

Persistent URL: http://purl.obolibrary.org/obo/SO_0002314

Alternate IDs: None

Subsets: None

Cross references: None

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2020-12-18 in commit dddaa2f

Most recent Git-era change: 2023-02-17 in commit 07b30b4

Number of changes: 2

Ontology neighborhood diagram

Ontology neighborhood for SO:0002314 Ontology neighborhood graph for SO:0002314 altered_gene_product_level. Parent, child, and related nodes can be activated to open their term pages. SO:0001536 functional_effect_variant SO:0001536 functional_effect_variant SO:0002314 altered_gene_product_level SO:0002314 altered_gene_product_level SO:0002315 increased_gene_product_level SO:0002315 increased_gene_product_level SO:0002316 decreased_gene_product_level SO:0002316 decreased_gene_product_level
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2023-02-17definition changedDefinition updated
Before: A sequence variant that alters the level of transcription of a gene.
After: A sequence variant that alters the level or amount of gene product produced. This high level term can be applied where the direction of level change (increased vs decreased gene product level) is unknown or not confirmed.
07b30b4
#612
2020-12-18createdTerm introduced into the editable ontology history
Initial label: altered_gene_product_level
Initial definition captured.
Initial parent: SO:0001536
dddaa2f
#501