Category:SO:0001179 ! U3 snoRNA
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id: SO:0001179
name: U3_snoRNA
def: "U3 snoRNA is a member of the box C/D class of small nucleolar RNAs. The U3 snoRNA secondary structure is characterised by a small 5' domain (with boxes A and A'), and a larger 3' domain (with boxes B, C, C', and D), the two domains being linked by a single-stranded hinge. Boxes B and C form the B/C motif, which appears to be exclusive to U3 snoRNAs, and boxes C' and D form the C'/D motif. The latter is functionally similar to the C/D motifs found in other snoRNAs. The 5' domain and the hinge region act as a pre-rRNA-binding domain. The 3' domain has conserved protein-binding sites. Both the box B/C and box C'/D motifs are sufficient for nuclear retention of U3 snoRNA. The box C'/D motif is also necessary for nucleolar localization, stability and hypermethylation of U3 snoRNA. Both box B/C and C'/D motifs are involved in specific protein interactions and are necessary for the rRNA processing functions of U3 snoRNA." [1]
comment: The definition is most of the old definition for snoRNA (SO:0000275).
synonym: "small nucleolar RNA U3" EXACT []
synonym: "snoRNA U3" EXACT []
synonym: "U3 small nucleolar RNA" EXACT []
synonym: "U3 snoRNA" EXACT []
xref: http://en.wikipedia.org/wiki/Small_nucleolar_RNA_U3 "wiki"
is_a: SO:0000593 ! C_D_box_snoRNA
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History of this term:
| Date Created | Date Last Edited | Date Obsoleted | Date Last Checked |
| 2007-11-09 | 2009-05-08 | 0000-00-00 | 2011-10-11 |
| [revision] | [revision] | [] |
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