insulator (CURRENT_SVN) |
|
|---|---|
| SO Accession: | SO:0000627 (SOWiki) |
| Definition: | A regulatory region that 1) when located between a CRM and a gene's promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region. |
| Synonyms: | INSDC_qualifier:insulator, insulator element, INSDC_feature:regulatory |
| DB Xrefs: | NCBI: cf |
| PMID: 12154228 | |
| SO: regcreative | |
| Parent: | cis_regulatory_module (SO:0000727) |
| Children: | boundary_element (SO:0002020) |
| enhancer_blocking_element (SO:0002190) | |
| insulator_binding_site (SO:0001460) | |
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