tmRNA (CURRENT_SVN) |
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|---|---|
| SO Accession: | SO:0000584 (SOWiki) |
| Definition: | A tmRNA liberates a mRNA from a stalled ribosome. To accomplish this part of the tmRNA is used as a reading frame that ends in a translation stop signal. The broken mRNA is replaced in the ribosome by the tmRNA and translation of the tmRNA leads to addition of a proteolysis tag to the incomplete protein enabling recognition by a protease. Recently a number of permuted tmRNAs genes have been found encoded in two parts. TmRNAs have been identified in eubacteria and some chloroplasts but are absent from archeal and Eukaryote nuclear genomes. |
| Synonyms: | 10Sa RNA, ssrA, INSDC_feature:tmRNA |
| DB Xrefs: | URL: http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00023 |
| Parent: | small_regulatory_ncRNA (SO:0000370) |
| Child: | tmRNA_region (SO:0000847) |
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