Sequence Ontology

A shared vocabulary for biological sequence features and annotations

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lncRNA

SO:0001877

Definition: A non-coding RNA generally longer than 200 nucleotides that cannot be classified as any other ncRNA subtype. Similar to mRNAs, lncRNAs are mainly transcribed by RNA polymerase II, are often capped by 7-methyl guanosine at their 5' ends, polyadenylated at their 3' ends and may be spliced.

Comments and references

Updated the definition of lncRNA (SO:0001877) from "A non-coding RNA over 200nucleotides in length." to "A non-coding RNA generally longer than 200 nucleotides that cannot be classified as any other ncRNA subtype. Similar to mRNAs, lncRNAs are mainly transcribed by RNA polymerase II, are often capped by 7-methyl guanosine at their 5' ends, polyadenylated at their 3' ends and may be spliced." See GitHub Issue #575

Definition references: HGNC:mw

Synonyms

ScopeValue
exactINSDC_qualifier:lncRNA
exactlncRNA_transcript
exactlong non-coding RNA
broadINSDC_feature:ncRNA

Identifiers and subsets

Accession: SO:0001877

Persistent URL: http://purl.obolibrary.org/obo/SO_0001877

Alternate IDs: None

Subsets: None

Cross references: http://www.gencodegenes.org/gencode_biotypes.html

History summary

Term history is reconstructed from the Git-era ontology files by comparing ontology classes across revisions. Earlier SVN-era changes will be added at a future date.

First seen in Git-era editable history: 2016-12-05 in commit 92e3cae

Most recent Git-era change: 2022-10-28 in commit 1908dd8

Number of changes: 5

Ontology neighborhood diagram

Ontology neighborhood for SO:0001877 Ontology neighborhood graph for SO:0001877 lncRNA. Parent, child, and related nodes can be activated to open their term pages. SO:0000655 ncRNA SO:0000655 ncRNA SO:0001877 lncRNA SO:0001877 lncRNA SO:0001904 antisense_lncRNA SO:0001904 antisense_lncRNA SO:0001463 lincRNA SO:0001463 lincRNA SO:0002131 sense_intronic_lncRNA SO:0002131 sense_intronic_lncRNA SO:0002132 sense_overlap_lncRNA SO:0002132 sense_overlap_lncRNA SO:0002381 bidirectional_promoter_lncRNA SO:0002381 bidirectional_promoter_lncRNA
The local DAG shows nearby parent, child, and related terms. Each node links to its own term page.

Relationships

Parents

Children

Change history

This timeline summarizes changes identified in SO’s GitHub commit history, including updates to labels, definitions, parent terms, synonyms, subsets, and obsoletion status. It is a best-effort reconstruction and may not include every change to a term. Since only history from GitHub is included at the moment, any term added before the migration from SVN to Git will show as being created in 2016. This will be addressed once SVN history is incorporated.

DateChangeSummaryEvidence
2022-10-28definition changedDefinition updated
Before: A non-coding RNA over 200nucleotides in length.
After: A non-coding RNA generally longer than 200 nucleotides that cannot be classified as any other ncRNA subtype. Similar to mRNAs, lncRNAs are mainly transcribed by RNA polymerase II, are often capped by 7-methyl guanosine at their 5' ends, polyadenylated at their 3' ends and may be spliced.
1908dd8
#575
2021-04-23label changedLabel changed from lnc_RNA to lncRNA
Before: lnc_RNA
After: lncRNA
296ecdb
#503
2018-01-26synonym addedSynonym added: INSDC_qualifier:lncRNA
Scope: exact
5fe48bd
2018-01-26synonym addedSynonym added: INSDC_feature:ncRNA
Scope: broad
5fe48bd
2016-12-05createdTerm introduced into the editable ontology history
Initial label: lnc_RNA
Initial definition captured.
Initial parent: SO:0000655
92e3cae