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insulator    (CURRENT_RELEASE)

SO Accession: SO:0000627 (SOWiki)
Definition: A regulatory region that 1) when located between a CRM and a gene's promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region.
Synonyms: INSDC_qualifier:insulator, insulator element, INSDC_feature:regulatory
DB Xrefs: NCBI: cf
PMID: 12154228  
SO: regcreative

Parent: cis_regulatory_module (SO:0000727)

Children: boundary_element (SO:0002020)
enhancer_blocking_element (SO:0002190)
insulator_binding_site (SO:0001460)
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Graph image for SO:0000627